NCT02544997
Breast Cancer Type: HR+ & HER2-negative, Triple Negative
Hormone Mutations: AR+, ER+, PR+
Other Mutations: EGFR, HER2, HER2-low
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 2
Drug Category: Tyrosine-Kinase Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 20 Years and older (Adult, Senior)
Location of Metastases:
Additional Notes: Must have an activated HER2 mutation or EGFR mutation/gene amplification or activated AR pathway
Exclusions: No prior history of pan-HER TKI including poziotinib for MBC; Documented leptomeningeal brain metastasis; Known brain metastases unless treated and stable; Patients with HER2+ breast cancer
https://ClinicalTrials.gov/show/NCT02544997