NCT03650894
Breast Cancer Type: HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+, AR+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 2
Drug Category: Immunotherapy, Therapeutic Antibody, Endocrine (Hormone Therapy
Key Eligibility Criteria:
Gender: Female
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients with TNBC must have tumors that are also AR+; Patients must be within 1 year following completion of curative-intent chemotherapy
Exclusions: Patients with active brain metastases or leptomeningeal metastases- see trial for details; Patients who have received more than 1 line of chemotherapy in the metastatic setting; Prior therapy with an anti-PD-1, -PD-L1, -PD-L, or- CTLA-4 agent or with bicalutamide, enzalutamide, or any other AR blocker
https://ClinicalTrials.gov/show/NCT03650894