NCT03718091
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: ATM, BRCA+, CDK, DNA damage repair mutations, MYC, FBXW7, CCNE1, ARID1A
Breast Cancer Tissue:
Recruitment Status: Active, not recruiting
Phase 2
Drug Category: Serine-Threonine Kinase Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 12 Years and older (Child, Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have tumors that express one of the mutations listed
Exclusions: Patients with known, untreated, unstable brain metastases that require treatment – see trial for details; Patients who have previously received treatment with an ATR inhibitor
https://ClinicalTrials.gov/show/NCT03718091