NCT05245500
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: MTAP
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 1|Phase 2
Drug Category: Misc Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have tumors that express a homozygous deletion of the MTAP gene
Exclusions: Patients with prior treatment of a PRMT5 or MAT2A inhibitor therapy; Patients with active brain metastases; Patients with leptomeningeal disease
https://ClinicalTrials.gov/show/NCT05245500