Into This World We're Thrown
NCT05057013
Breast Cancer Type: Triple Negative
Hormone Mutations:
Other Mutations: HER3
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 1|Phase 2
Drug Category: Therapeutic Antibody
Gender: All
Age: 16 Years and older (Child, Adult, Older Adult)
Location of Metastases:
Additional Notes:
Exclusions: Patients with symptomatic brain or leptomeningeal metastases – see trial for details
https://ClinicalTrials.gov/show/NCT05057013
NCT04383210
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: HER3
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 2
Drug Category: Therapeutic Antibody
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patient must have a tumor that expresses an NRG1 gene fusion
Exclusions: Patients with untreated or symptomatic brain metastases that require treatment – see trial for details; Patients with prior treatment of ERBB3/HER3 directed therapy
https://ClinicalTrials.gov/show/NCT04383210