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Listed below are over 600+ promising drugs currently in pre-clinical or clinical trials for advanced or metastatic breast cancer. The majority of the drugs listed are targeted therapies which target ONLY cancer cells. In order to receive targeted therapy, a patient needs to provide a tumor sample for genomic testing. If the tumor carries certain mutations (e.g. HER2+ or AR+), these targeted drugs can exploit those mutations and stop the spread of cancer.
Unlike targeted therapies, chemotherapy and some immunotherapies are less precise and attack both normal cells AND cancer cells. When a drug attacks normal cells, it can lead to potentially worse side effects. However, a combination of therapies may result in a better outcome for the patient. Any patient can receive non-targeted drugs regardless of the mutations carried by their tumor.
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Table of Promising Drugs for Breast Cancer (Updated Jan 2019)
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