NCT02675946
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 1
Drug Category: Misc Inhibitor, Immunotherapy, Therapeutic Antibody
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult), Senior)
Location of Metastases:
Additional Notes: Breast cancer patients are not eligible for the expansion phase
Exclusions: Patients with known active central nervous system metastases and/or leptomeningeal disease; Patients with bone metastases with prior history of pathologic fracture; Patients with prior exposure to a WNT inhibitor (except Roll-over cohort); Patients with prior exposure to PD-1 & PD-L1/2 inhibitors
https://ClinicalTrials.gov/show/NCT02675946