NCT03054363: Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer

Breast Cancer Type: HER2+
Hormone Mutations: ER+, PR+
Other Mutations: 
Breast Cancer Tissue: 
Recruitment Status: Active, not recruiting
Phase 1|Phase 2
Drug Category: Tyrosine-Kinase Inhibitor, Serine-Threonine Kinase Inhibitor, Endocrine (Hormone) Therapy

Key Eligibility Criteria:

Gender: Female
Age: 18 Years to 100 Years (Adult, Senior)
Location of Metastases: Brain
Additional Notes: Patients must also be either ER+ or PR+
Exclusions: Patients with previously treated progressing brain metastases; stable brain metastases allowed- check trial for details

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