NCT04029688
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 1|Phase 2
Drug Category: Misc Inhibitor, Chemotherapy
Key Eligibility Criteria:
Gender: All
Age: up to 30 Years (Child, Adult)
Location of Metastases:
Additional Notes: Breast cancer patients are only eligible for Part 1 (single-agent therapy) dose escalation of the study
Exclusions: Patients with symptomatic CNS metastases that result in a neurologically unstable clinical state or require treatment; Patients with prior treatment with a MDM2 antagonist or venetoclax (if eligible for the venetoclax arm of study)
https://ClinicalTrials.gov/show/NCT04029688