NCT04123366
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: DNA damage repair mutations
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 2
Drug Category: Misc Inhibitor, Immunotherapy, Therapeutic Antibody
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patient must be refractory to prior platinum therapy (e.g. cisplatin, carboplatin, or oxaliplatin)
Exclusions: Patients with either germline (genetic or somatic BRCA mutation; Patients with known central nervous system (CNS) metastases and/or leptomeningeal disease; Patients who received olaparib (or any other PARP inhibitor) or prior anti-PD-1/PD-L1/2, -CTLA4, -OX40 or -CD137 agent
https://ClinicalTrials.gov/show/NCT04123366