NCT04225117
Breast Cancer Type: HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 2
Drug Category: Therapeutic Antibody
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have progressed or relapsed on at least 1 prior cytotoxic regimen (taxane or anthracycline) in the metastatic setting and TNBC patients must have also progressed on anti-PD-1/L1 treatments
Exclusions: Patients with active unstable central nervous system (CNS) metastases that require treatment – see trial for details; Patients with leptomeningeal disease; Patients who received more than 2 prior lines of cytotoxic therapy in the metastatic setting; Patients with prior treatment with enfortumab vedotin or other monomethyl auristatin E (MMAE) based antibody-drug conjugates
https://ClinicalTrials.gov/show/NCT04225117