NCT04267939
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: DNA damage repair mutations
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 1
Drug Category: Serine-Threonine Kinase Inhibitor, Misc Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have tumor(s that express DNA damage repair mutations; Breast cancer patients are only eligible for the dose escalation phase (Part A)
Exclusions: Patients with prior treatment of an ATR Inhibitor
https://ClinicalTrials.gov/show/NCT04267939