NCT04291079: SRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors

Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: 
Breast Cancer Tissue: 
Recruitment Status: Recruiting
Phase 1
Drug Category: Immunotherapy, Therapeutic Antibody

Key Eligibility Criteria:

Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases: 
Additional Notes: Patient must have either progressive or stable disease (e.g., not improving, but not worsening, clinically or radiographically after at least 3 cycles of treatment) with an anti-PD-L1 antibody therapy (alone or in combination with chemotherapy approved for that tumor type)
Exclusions: Patient has symptomatic or uncontrolled brain metastases or leptomeningeal disease; Patients who have NOT received their most recent dose of anti-PD-(L)1 antibody therapy within 6 months enrollment

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