NCT04796012
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Not yet recruiting
Phase 2
Drug Category: Therapeutic Antibody, Immunotherapy, Chemotherapy
Key Eligibility Criteria:
Gender: All
Age: 6 Years to 30 Years (Child, Adult)
Location of Metastases:
Additional Notes:
Exclusions: Patients with brain metastasis affecting the brainstem, midbrain, pons, or cerebellum, or within 10 mm of optic nerve; Patients with a history of leptomeningeal disease; Patients with prior treatment of CD137 agonists or immune checkpoint blockade therapies to include all anti-PD-1, and anti-PD-L1 therapeutic antibodies (e.g. Keytruda/pembrolizumab, Tecentriq/atezolizumab)
https://ClinicalTrials.gov/show/NCT04796012