NCT04975308
Breast Cancer Type: HR+ & HER2-negative
Hormone Mutations: ER+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 3
Drug Category: Endocrine (Hormone Therapy, Serine-Threonine Kinase Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have progression on or after an aromatase inhibitor alone or in combination with a CDK4/6 inhibitor
Exclusions: Patients with prior treatment of chemotherapy (except for neoadjuvant/ adjuvant chemotherapy, fulvestrant, or any investigational-ER-directed therapy (including SERDs & non-SERDs), or any PI3K-, mTOR- or AKT- inhibitor; Patients with symptomatic or untreated brain metastasis; Patients with leptomeningeal disease
https://ClinicalTrials.gov/show/NCT04975308