NCT05006794
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations:
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 1
Drug Category: Therapeutic Antibody, Chemotherapy, Misc Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have progressed on at least 1 prior standard therapeutic regimen; Patients with triple negative breast cancer (TNBC) are eligible for the dose expansion phase
Exclusions: Patients with unstable untreated symptomatic brain metastases – see trial for details; Patients with a history of leptomeningeal disease; Patients with prior treatment of any myeloid cell leukemia 1 (MCL1) inhibitor; For dose expansion phase, TNBC patients with more than 1 prior chemotherapy regimen
https://ClinicalTrials.gov/show/NCT05006794