NCT05025735
Breast Cancer Type: HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: PI3K
Breast Cancer Tissue:
Recruitment Status: Recruiting
Phase 2
Drug Category: Misc Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 18 Years to 65 Years (Adult, Older Adult)
Location of Metastases:
Additional Notes: Patients must have had prior treatment with a CDK4/6 inhibitor (e.g. palbociclib/Ibrance, abemaciclib/Verzenio, ribociclib/Kisqali)
Exclusions: Patients who have received prior treatment with chemotherapy, fulvestrant, any PI3K, mTOR or AKT inhibitor (e.g. Piqray/alpelisib, Afinitor/everolimus) in the metastatic setting; Patients with untreated unstable symptomatic brain metastases – see trial for details
https://ClinicalTrials.gov/show/NCT05025735