NCT05120960
Breast Cancer Type: HER2+, HR+ & HER2-negative, Triple Negative
Hormone Mutations: ER+, PR+
Other Mutations: MET
Breast Cancer Tissue:
Recruitment Status: Not yet recruiting
Phase 1
Drug Category: Tyrosine-Kinase Inhibitor
Key Eligibility Criteria:
Gender: All
Age: 18 Years and older (Adult, Older Adult)
Location of Metastases: Brain
Additional Notes: Breast cancer patients are eligible for the dose exploration (phase 1a, group A of the study); Participants must have at least 1 measurable brain metastasis present; Participants must require surgical resection; For patients with prior whole brain radiation therapy or SRS, progression in any measurable brain metastasis must have occurred at least 1 month after the end of radiation therapy
Exclusions:
https://ClinicalTrials.gov/show/NCT05120960